Numerical simulation of Microfluidic devices

Abstract

Microfluidic devices present a unique powerful platform for working with living cells. The length and volume scales of these devices in miniaturize system make it possible to perform detailed analyses with several advantages. The small volume facilitates response detection by effectively increasing the local concentration of the analyte. Microfluidic lab-on-chip technologies represent a revolution in laboratory experimentation, bringing the benefits of miniaturization to many researchers. This project aim on simulation of the fluid flow, the mixing concentration distribution to the interaction of protein and other biological reagents, fluid flow pressure, and fluid flow velocity field with designing Micromixer, Microchannel and Microchamber for Microfluidic devices using simulation software COMSOL Multiphysics 3.5. Fluid flow patterns, concentration distribution and velocity field were observed by using simulation software. Fluid flow patterns obtained at the junction and The component consists of a PDMS microchannel to give a continuous open circuit flow, a 0.7μm/s was obtained.